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Zoloft is an SSRI medication that has been proven to alleviate depression, but it comes with its own share of harsh side effects. Zoloft is a great anti-depressant, but it is known for its side effects profile. Some people snort Zoloft which is an illegal thing to do. The technical name for Zoloft is Sertraline. It has 44% bioavailability, 98.5% protein binding, hepatic metabolism, a half-life of approximately 26 hours, renal excretion, pregnancy category C, legal status of only prescription, and an oral route of administration. It is the largest anti-depressant in the world with about 30 million prescriptions. It has also been used to treat a variety of other conditions like major depression, obsessive-compulsive disorder, posttramautic stress disorder, premenstrual dysphoric disorder, panic disorder, and social phobia.
There are several disorders for which Zoloft is effective. It has good comparison with tricyclic anti-depressants and other anti-depressants. Its use in social phobia, panic disorder, and premenstrual dysphoric disorder is pronounced. There are some adverse effects like overdosage, sexual side effects, and suicidality. There is also the possibility of negative effects from quitting the medication. It is an SSRI. There is some controversy with how it has been advertised to consumers. A commercial for Zoloft by Pfizer asserted that depression came from an imbalance of natural chemicals in the brain with how different nerve cells were affected by each other. There is no evidence to support this theory according to PLoS Medicine, and Pfizer was consequently reprimanded by consumers for using that phrase. SSRI discontinuation syndrome and other negative effects for taking Zoloft are reported fairly frequently so consumers should be forewarned before taking this medication.
There is no guarantee that Zoloft will work to correct depression even with commercials to that effect. Zoloft is a strong anti-depressant with a litany of side effects and possible side effects when you get off the medication.